Did You Know? Important Notes on EO (Ethylene Oxide) Sterilization

Did You Know?

🛑 EO Sterilization – Aeration Time
In Ethylene Oxide (EO) sterilization, the aeration step is mandatory to remove residual EO from instruments after sterilization, ensuring safety for patients and healthcare staff.
So, how long should aeration last? Let’s review recommendations from regulatory bodies and device manufacturers 👇
🔎 Recommendations and International Standards
 
1️⃣ CDC – Ethylene Oxide Gas Sterilization | Infection Control
“Mechanical aeration for 8–12 hours at 50–60°C removes residual EO absorbed in materials in contact.”
 
2️⃣ EN 1422:2014 – EO Sterilizers
“When aeration is performed in the sterilizer chamber, residual EO in sterilized products is reduced to levels compliant with EN ISO 10993-7:2008. The removal of absorbed EO depends on product characteristics, packaging, and components.”
📎 Source: EN 1422:2014
 
3️⃣ Manufacturer Instructions – Medical Devices
💡 Manufacturers know their products best, so always follow their instructions to ensure maximum safety. Recommended aeration times vary:
✅ KARL STORZ: 12 hours
📎 Source: KARL STORZ IFU
✅ RICHARD WOLF: 6 hours
✅ AESCULAP®: Minimum 8 hours when using sterilization trays
 
📌 Key point: There is no fixed aeration time for all devices. Aeration must follow manufacturer instructions and international standards to ensure:
✔ Residual EO is within safe limits
✔ Patient safety
✔ Healthcare staff safety
 
❓ Is your hospital using an EO sterilizer?
Make sure the aeration time is set correctly to protect patients and staff ❤️
 
👉 Follow us for more updates on infection control and international sterilization standards.
 
Content Responsibility: Mr. Nguyen Tien Nam
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